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CS-W001157 4
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tert-Butyl (R)-(3-oxobutan-2-yl)carbamate

  • CAS No. 1350713-44-8

  • Cat. No. CS-0608818
  • Molecule weight187.24
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (R)-(3-oxobutan-2-yl)carbamate|CS-0608818

Structure of 1350713-44-8

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General Information

  • CAS No. 1350713-44-8
  • Cat. No. CS-0608818
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₇NO₃
  • Molecular Weight 187.24
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)N[C@H](C)C(C)=O

Description

This chiral carbamate features a tert-butyl-protected (R)-3-oxobutan-2-yl group, enabling direct incorporation into asymmetric synthesis workflows. The ketone moiety provides a handle for stereoselective transformations, while the bench-stable tert-butyl carbamate offers reliable protection under standard conditions.

Application

tert-Butyl (R)-(3-oxobutan-2-yl)carbamate serves as a chiral building block for asymmetric synthesis, enabling the efficient construction of β-keto amine motifs. Its stability under standard reaction conditions and compatibility with diverse transformations—such as reductive amination, enolate formation, and coupling reactions—facilitates streamlined access to complex intermediates in medicinal chemistry and natural product synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   55.4
  • LogP   1.4886
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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