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CS-W001157 4
Total: USD 88.00

H2N-PEG2-CH2COOH

  • CAS No. 134978-97-5

  • Cat. No. CS-W006524
  • Purity≥97%
  • MDL No.MFCD13185897

*For research and further manufacturing use only, not for direct human use.

H2N-PEG2-CH2COOH|CS-W006524

Structure of 134978-97-5

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General Information

  • CAS No. 134978-97-5
  • Cat. No. CS-W006524
  • Purity ≥97%
  • MDL No. MFCD13185897
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₃NO₄
  • Molecular Weight 163.17
  • Synonym(s) None
  • SMILES O=C(O)COCCOCCN

Description

Zein is a prolamine and an alcohol soluble protein present in maize endosperm cells. Zein is a 20kDa structural protein and is encoded by the gene mapped on the short arm of maize chromosome 7. This protein lacks essential amino acids, such as lysine and tryptophan. Therefore, it has a poor nutritional value.Zein has been used as a biopolymer in electrospinning technique. It has also been used to blend starch involved in the manufacture of thermoplastic material.

Application

H₂N-PEG₂-CH₂COOH serves as a versatile bifunctional linker for conjugation and polymer synthesis, combining the stability of a short PEG spacer with amine and carboxylic acid termini. The primary amine enables efficient coupling to activated esters or aldehydes, while the terminal carboxylic acid facilitates amide bond formation or further derivatization. Its balanced solubility and robustness under standard reaction conditions make it ideal for peptide modification, bioconjugation, and the construction of functionalized polymers in medicinal chemistry workflows.

Synthesis

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    • In-stock
      H2N-PEG2-CH2COOH|CS-W006524
      134978-97-5

    References

    • Organic Letters, , vol. 7, # 9 p. 1699 - 1702
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    References

    • Organic and Biomolecular Chemistry, , vol. 6, # 17 p. 3065 - 3078
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    References

    • WO2006/82245 A1, ; Page/Page column 357 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   81.78
  • LogP   -0.9371
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   7

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