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CS-W001157 4
Total: USD 88.00

Boc-NH-PEG5-CH2CH2COOH

  • CAS No. 1347750-78-0

  • Cat. No. CS-0040953
  • Purity≥97%
  • MDL No.MFCD24539478

*For research and further manufacturing use only, not for direct human use.

Boc-NH-PEG5-CH2CH2COOH|CS-0040953

Structure of 1347750-78-0

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General Information

  • CAS No. 1347750-78-0
  • Cat. No. CS-0040953
  • Purity ≥97%
  • MDL No. MFCD24539478
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₃₅NO₉
  • Molecular Weight 409.47
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NCCOCCOCCOCCOCCOCCC(O)=O

Description

Boc-NH-PEG5-CH2CH2COOH features a tert-butoxycarbonyl-protected amine terminus linked to a five-ethylene glycol spacer, culminating in a terminal carboxylic acid. This bifunctional scaffold enables site-specific conjugation via amide bond formation, while the PEG5 chain imparts solubility and reduces aggregation in aqueous environments. Ideal for bioconjugation workflows requiring stability and controlled functional group presentation.

Application

Boc-NH-PEG5-CH₂CH₂COOH serves as a versatile bifunctional linker for conjugation and solid-phase synthesis. The Boc-protected amine enables stable storage and orthogonal deprotection, while the terminal carboxylic acid facilitates efficient coupling via standard amide bond formation. The five-ethylene glycol (PEG5) spacer provides enhanced solubility and reduced aggregation, improving accessibility in aqueous and biological environments. This compound functions reliably in peptide modification, antibody-drug conjugate assembly, and functionalized nanoparticle synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   121.78
  • LogP   1.0688
  • H_Acceptors   8
  • H_Donors   2
  • Rotatable_Bonds   18

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