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Structure of 1331945-14-2
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This boronic acid features a fluorinated aryl ring paired with a hydroxymethyl-bearing boronate group, enabling efficient Suzuki-Miyaura coupling under standard conditions. The ortho-fluoro substituent enhances reactivity and metabolic stability, while the hydroxymethyl handle facilitates downstream functionalization. Bench-stable and moisture-tolerant, it integrates seamlessly into complex molecule synthesis workflows.
(2-Fluoro-4-(hydroxymethyl)phenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. The hydroxymethyl group provides a handle for downstream functionalization, while the boronic acid moiety exhibits excellent bench stability and compatibility with diverse reaction conditions. Its ortho-fluorine substituent enhances reactivity and facilitates selective transformations, making it a practical choice for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P210-P261-P264-P271-P280-P302+P352-P304+P340-P362-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: