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Structure of 1331850-50-0
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4-Iodo-3-methoxypyridine is a bench-stable pyridine derivative featuring a para-iodo and ortho-methoxy substitution pattern. This combination delivers enhanced reactivity in cross-coupling processes, enabling efficient C–C bond formation under standard conditions. The electron-rich methoxy group stabilizes the transition state, while the iodide serves as a high-reactivity handle for palladium-catalyzed transformations.
4-Iodo-3-methoxypyridine serves as a versatile building block in cross-coupling reactions, enabling efficient construction of biaryl and heterocyclic architectures. The iodide group facilitates palladium-catalyzed coupling with boronic acids, amines, and other nucleophiles under standard conditions. Its methoxy substituent provides moderate electron-donating character and enhances solubility, while the pyridine core offers predictable reactivity and stability for bench-scale synthesis. This compound functions reliably in medicinal chemistry campaigns and process development workflows.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331
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Precautionary Statements : P260-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501
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Lot numbers can be found on the outside label of a product: