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Structure of 131747-46-1
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This trifluoromethyl-substituted pyridine derivative features a reactive benzylic alcohol group, enabling direct functionalization or coupling reactions. The electron-deficient pyridine ring enhances compatibility with nucleophilic transformations, while the trifluoromethyl moiety imparts enhanced metabolic stability and lipophilicity. This combination makes the compound valuable in medicinal chemistry and agrochemical synthesis.
(4-(Trifluoromethyl)pyridin-2-yl)methanol serves as a versatile building block in medicinal chemistry, enabling efficient incorporation of a polar trifluoromethyl-pyridyl moiety. The alcohol functionality facilitates straightforward derivatization—such as oxidation to the carboxaldehyde or esterification—while maintaining compatibility with common protecting group strategies. Its bench-stable nature and tolerance to diverse reaction conditions make it well-suited for iterative synthesis workflows targeting bioactive heterocycles and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: