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(R)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-((tert-butoxycarbonyl)amino)butanoic acid

  • CAS No. 131570-57-5

  • Cat. No. CS-0099798
  • Purity≥96%
  • MDL No.MFCD00798625

*For research and further manufacturing use only, not for direct human use.

(R)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-((tert-butoxycarbonyl)amino)butanoic acid|CS-0099798

Structure of 131570-57-5

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General Information

  • CAS No. 131570-57-5
  • Cat. No. CS-0099798
  • Purity ≥96%
  • MDL No. MFCD00798625
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₄H₂₈N₂O₆
  • Molecular Weight 440.49
  • Synonym(s) Boc-D-Dab(Fmoc)-OH
  • SMILES O=C(O)[C@H](NC(OC(C)(C)C)=O)CCNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O

Description

(R)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-((tert-butoxycarbonyl)amino)butanoic acid is a chiral building block featuring a fluorenylmethyl carbamate (Fmoc) group and a tert-butyl carbamate (Boc) side chain. This combination enables orthogonal protection in peptide synthesis, facilitating selective deprotection sequences. The molecule's bench-stable nature supports reliable handling under standard conditions.

Application

(R)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-((tert-butoxycarbonyl)amino)butanoic acid serves as a key chiral building block in peptide synthesis, enabling the efficient construction of complex peptide architectures. The Fmoc group provides orthogonal protection for the α-amino function, while the Boc-labeled side chain amine allows selective deprotection and functionalization. Its bench-stable nature and compatibility with standard coupling conditions facilitate reliable, high-yield transformations in both solid-phase and solution-phase workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   113.96
  • LogP   3.8931
  • H_Acceptors   5
  • H_Donors   3
  • Rotatable_Bonds   7

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