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Structure of 1314743-49-1
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This thiourea derivative features a sterically hindered cyclohexylpyrrolidine scaffold paired with electron-deficient trifluoromethylated aryl groups, delivering enhanced stability and tunable polarity. The combination enables efficient integration into functionalized molecular architectures for advanced synthetic applications.
1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1R,2R)-2-(pyrrolidin-1-yl)cyclohexyl]thiourea serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocyclic scaffolds. Its trifluoromethylated aryl group enhances metabolic stability and lipophilicity, while the chiral cyclohexyl-pyrrolidine motif provides defined stereochemistry for structure-activity studies. The thiourea functionality facilitates hydrogen bonding interactions in target binding and supports efficient purification via crystallization or chromatography. This compound exhibits bench stability and tolerance to diverse reaction conditions, making it suitable for iterative synthesis campaigns in drug discovery.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H413
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Precautionary Statements : P264-P270-P273-P330-P501
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Lot numbers can be found on the outside label of a product: