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Structure of 1289514-24-4
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N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(1R,2R)-2-(1-piperidinyl)cyclohexyl]thiourea features a sterically hindered cyclohexylpiperidine moiety paired with electron-deficient trifluoromethyl aryl groups, enabling high binding affinity in target-directed pharmacological studies. This bench-stable thiourea integrates readily into probe design workflows requiring enhanced metabolic resistance and membrane permeability.
N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(1R,2R)-2-(1-piperidinyl)cyclohexyl]thiourea serves as a versatile building block for bioactive molecule synthesis, leveraging the electron-withdrawing trifluoromethyl groups to enhance metabolic stability and membrane permeability. The thiourea core enables robust hydrogen bonding and coordination in target engagement, while the chiral cyclohexylpiperidine moiety provides conformational rigidity beneficial for structure-activity studies. Its bench-stable nature and compatibility with standard coupling protocols facilitate efficient incorporation into pharmaceutical scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: