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Structure of 1240466-16-3
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N-[(1R,2R)-2-[Bis(phenylmethyl)amino]cyclohexyl]-N'-[3,5-bis(trifluoromethyl)phenyl]thiourea features a rigid chiral cyclohexyl scaffold paired with sterically demanding benzylamino groups and an electron-deficient trifluoromethylated aryl thiourea. This configuration enables selective binding in asymmetric catalysis and molecular recognition applications.
N-[(1R,2R)-2-[Bis(phenylmethyl)amino]cyclohexyl]-N'-[3,5-bis(trifluoromethyl)phenyl]thiourea serves as a versatile chiral scaffold in medicinal chemistry, enabling the construction of complex heterocyclic systems through its bifunctional thiourea motif. The molecule exhibits enhanced stability and solubility in organic media, facilitating straightforward purification and compatibility with standard coupling protocols. Its trifluoromethylated aryl group imparts favorable lipophilic character and metabolic resistance, making it suitable for probe development and lead optimization campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: