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Structure of 131467-02-2
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2-Chloro-4-vinylpyrimidine, stabilized with TBC, features a reactive vinyl group enabling efficient coupling in cross-coupling and polymerization reactions. The electron-deficient pyrimidine core enhances reactivity, while the stabilizing additive ensures shelf stability under ambient conditions.
2-Chloro-4-vinylpyrimidine (stabilized with TBC) serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its reactive vinyl and chloropyrimidine functionalities. The stabilizer TBC prevents polymerization during storage, ensuring bench stability and reliable performance in Suzuki, Stille, and Negishi coupling protocols. Its functional group tolerance and ease of purification make it ideal for constructing complex scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 1760
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H227-H302-H314-H318
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Precautionary Statements : P210-P260-P264-P270-P280-P301+P330+P331-P304+P340-P363-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: