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CS-W001157 4
Total: USD 88.00

NSC 13199

  • CAS No. 5424-21-5

  • Cat. No. CS-D1522
  • Purity≥97%
  • MDL No.MFCD00006064

*For research and further manufacturing use only, not for direct human use.

NSC 13199|CS-D1522

Structure of 5424-21-5

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General Information

  • CAS No. 5424-21-5
  • Cat. No. CS-D1522
  • Purity ≥97%
  • MDL No. MFCD00006064
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄Cl₂N₂
  • Molecular Weight 163.00
  • Synonym(s) 2,4-Dichloro-6-methylpyrimidine; 2,6-Dichloro-4-methylpyrimidine; 6-Methyl-2,4-dichloropyrimidine; Pyrimidine, 2,4-dichloro-6-methyl-
  • SMILES CC1=CC(Cl)=NC(Cl)=N1

Description

DBCO-NHCO-PEG4-NHS ester is a PEG linker containing NHS ester that is able to react specifically and efficiently with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and can also provide a long and flexible connection that minimizes steric hindrance during ligation. DBCO is commonly used for copper-free Click Chemistry reactions.

Synthesis

  • Route1

    References

    • Hung; Werbel Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 3 p. 741 - 744
  • Route2

    References

    • Yakugaku Zasshi, , vol. 70, p. 137 Chem.Abstr., , p. 5886
  • Route3

    References

    • Yakugaku Zasshi, , vol. 70, p. 137 Chem.Abstr., , p. 5886

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3263
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314-H318
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   25.78
  • LogP   2.09182
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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