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Structure of 1314398-21-4
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tert-Butyl (2,2-difluoro-3-hydroxypropyl)carbamate features a difluorinated propyl backbone with a hydroxyl group at the terminal position, enabling selective derivatization in synthetic workflows. The tert-butyl carbamate moiety provides stable protection under standard conditions, while the electron-withdrawing fluorine atoms enhance functional group compatibility and metabolic stability in complex molecular architectures.
tert-Butyl (2,2-difluoro-3-hydroxypropyl)carbamate serves as a stable, bench-friendly building block for fluorinated alcohols and β-fluorinated carbonyl precursors. The difluoro group enhances metabolic stability, while the hydroxyl functionality enables efficient derivatization via esterification or ether formation. Its tert-butyl carbamate moiety provides orthogonal protection, facilitating selective deprotection under mild acidic conditions. This compound functions effectively in multistep synthesis of fluorinated scaffolds relevant to medicinal chemistry and agrochemical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: