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Structure of 753023-57-3
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tert-Butyl [1-(2-hydroxyethyl)cyclopropyl]carbamate is a bench-stable, moisture-tolerant carbamate protecting group ideal for amino-functionalized cyclopropane derivatives. This reagent enables selective N-alkylation and late-stage functionalization in complex molecule synthesis, leveraging the cyclopropyl scaffold's conformational rigidity to control stereochemistry during coupling reactions.
tert-Butyl [1-(2-hydroxyethyl)cyclopropyl]carbamate serves as a stable, bench-friendly building block for cyclopropyl-containing scaffolds. The carbamate group enables mild deprotection under acidic conditions, while the pendant hydroxyl facilitates downstream derivatization via etherification or oxidation. Its compatibility with standard coupling and protection protocols makes it valuable in medicinal chemistry campaigns requiring rigid, three-membered ring motifs.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: