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CS-W001157 4
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(2-Amino-1,3-thiazol-5-yl)methanol

  • CAS No. 131184-73-1

  • Cat. No. CS-0060290
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(2-Amino-1,3-thiazol-5-yl)methanol|CS-0060290

Structure of 131184-73-1

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General Information

  • CAS No. 131184-73-1
  • Cat. No. CS-0060290
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₆N₂OS
  • Molecular Weight 130.17
  • Synonym(s) 5-Thiazolemethanol, 2-amino-
  • SMILES C1=C(CO)SC(=N)N1

Application

(2-Aminothiazol-5-yl)methanol serves as a versatile building block for thiazole-based heterocycles, enabling direct functionalization at the 5-position. Its primary amine and hydroxymethyl groups offer orthogonal reactivity, facilitating coupling reactions, derivatization, and incorporation into pharmaceutical scaffolds. The compound exhibits good bench stability and compatibility with standard purification techniques, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.

Synthesis

  • Route1

    References

    • Farmaco, , vol. 44, # 11 p. 1011 - 1030
  • Route2
    • null|null
      765-34-4
    • ~%
    • In-stock
      (2-Amino-1,3-thiazol-5-yl)methanol|CS-0060290
      131184-73-1

    References

    • US6265553 B1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   59.14
  • LogP   0.2176
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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