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CS-W001157 4
Total: USD 88.00

2-Aminonicotinaldehyde

  • CAS No. 7521-41-7

  • Cat. No. CS-M0437
  • Purity≥98%
  • MDL No.MFCD01830382

*For research and further manufacturing use only, not for direct human use.

2-Aminonicotinaldehyde|CS-M0437

Structure of 7521-41-7

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General Information

  • CAS No. 7521-41-7
  • Cat. No. CS-M0437
  • Purity ≥98%
  • MDL No. MFCD01830382
  • Storage -20°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₆N₂O
  • Molecular Weight 122.13
  • Synonym(s) None
  • SMILES O=CC1=C(N)N=CC=C1

Description

2-Aminonicotinaldehyde features a strategically positioned amino group adjacent to the aldehyde functionality, enabling direct incorporation into heterocyclic scaffolds. This electron-rich moiety facilitates efficient coupling reactions and serves as a key intermediate in the synthesis of bioactive nitrogen-containing compounds.

Application

2-Aminonicotinaldehyde serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through straightforward condensation and cyclization reactions. Its ortho-amino and aldehyde functionalities offer complementary reactivity for rapid scaffold diversification, particularly in pyridine- and quinoline-based frameworks. The compound exhibits good bench stability and facilitates efficient purification, making it well-suited for iterative synthesis campaigns in API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   55.98
  • LogP   0.4763
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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