4-Chloro-6H,7H,8H-pyrimido[5,4-b][1,4]oxazine

Name: 4-Chloro-6H,7H,8H-pyrimido[5,4-b][1,4]oxazine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1309377-79-4
Cat. No. CS-0308366
Purity≥95%
MDL No.MFCD20688584

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Chloro-6H,7H,8H-pyrimido[5,4-b][1,4]oxazine|CS-0308366

Structure of 1309377-79-4

Size

Price

Quantity

* Please select Quantity before adding items.

Description

4-Chloro-6H,7H,8H-pyrimido[5,4-b][1,4]oxazine is a heterocyclic scaffold featuring a fused pyrimidine-oxazine core with a chlorine substituent at the 4-position. This electron-deficient framework enables direct incorporation into medicinal chemistry campaigns, serving as a rigid bioisostere in kinase inhibitor design. The compound exhibits enhanced metabolic stability and favorable solubility profiles under standard conditions.

Application

4-Chloro-6H,7H,8H-pyrimido[5,4-b][1,4]oxazine serves as a versatile heterocyclic building block for medicinal chemistry and synthetic organic applications. Its chlorine substituent enables nucleophilic substitution reactions under mild conditions, facilitating the introduction of diverse amine- and thiol-containing functionalities. The scaffold exhibits good bench stability and compatibility with common protecting group strategies, making it well-suited for modular synthesis of complex nitrogen-containing systems.

General Information

CAS No. 1309377-79-4
Cat. No. CS-0308366
Purity ≥95%
MDL No. MFCD20688584
Storage -20°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₆ClN₃O
Molecular Weight 171.58
Synonym(s) 4-chloro-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazine
SMILES ClC1=C2OCCNC2=NC=N1

Computational Chemistry Data

TPSA 47.04
LogP 0.9343
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyrimidine compounds

Building Blocks Skeleton Aliphatic heterocycle compounds Other aliphatic heterocycles compounds

Key Words

1309377-79-4 sigma1309377-79-4 manufacturer1309377-79-4 price1309377-79-4 structure1309377-79-4 SDSbuy 1309377-79-41309377-79-4 supplier1309377-79-4 uses1309377-79-4 molecular weightprice of 1309377-79-41309377-79-4 chemical name formula of 1309377-79-4

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

4-Chloro-6H,7H,8H-pyrimido[5,4-b][1,4]oxazine

CAS No. 1309377-79-4

Recommended Products