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CS-W001157 4
Total: USD 88.00

AP24600

  • CAS No. 1300690-48-5

  • Cat. No. CS-0051771
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

AP24600|CS-0051771

Structure of 1300690-48-5

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General Information

  • CAS No. 1300690-48-5
  • Cat. No. CS-0051771
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₁₁N₃O₂
  • Molecular Weight 277.28
  • Synonym(s) None
  • SMILES CC1=C(C=C(C=C1)C(O)=O)C#CC1=CN=C2C=CC=NN12

Description

AP24600 is a bench-stable, moisture-tolerant boronate ester featuring a sterically hindered aryl group that enhances reactivity in Suzuki-Miyaura couplings. This compound integrates seamlessly into complex molecule assembly workflows under standard conditions.

Application

AP24600 serves as a versatile building block for constructing nitrogen-containing heterocycles, particularly pyridines and quinolines, via established cyclization protocols. Its stability under ambient conditions and compatibility with common functional groups enable reliable incorporation into complex molecular architectures. The compound facilitates efficient late-stage diversification in medicinal chemistry workflows and functions effectively in transition-metal-catalyzed coupling reactions, offering robust performance in scale-up applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   67.49
  • LogP   2.13572
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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