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CS-W001157 4
Total: USD 88.00

3-Ethynyl-Imidazo[1,2-b]pyridazine

  • CAS No. 943320-61-4

  • Cat. No. CS-M1484
  • Purity≥98%
  • MDL No.MFCD17012027

*For research and further manufacturing use only, not for direct human use.

3-Ethynyl-Imidazo[1,2-b]pyridazine|CS-M1484

Structure of 943320-61-4

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General Information

  • CAS No. 943320-61-4
  • Cat. No. CS-M1484
  • Purity ≥98%
  • MDL No. MFCD17012027
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅N₃
  • Molecular Weight 143.15
  • Synonym(s) 3-Ethynylimidazo[1,2-b]pyridazine
  • SMILES C#CC1=CN=C2C=CC=NN21

Description

3-Ethynyl-Imidazo[1,2-b]pyridazine features a reactive terminal alkyne appended to a rigid, electron-deficient imidazopyridazine core. This combination enables efficient copper-catalyzed click conjugation while maintaining stability under standard handling conditions. The scaffold serves as a valuable building block in bioconjugation and medicinal chemistry applications.

Application

3-Ethynyl-imidazo[1,2-b]pyridazine serves as a versatile building block for transition-metal-catalyzed coupling reactions, enabling efficient access to substituted heterocycles via Sonogashira and Glaser-type transformations. Its terminal alkyne functionality exhibits excellent bench stability and compatibility with diverse functional groups, facilitating straightforward purification and integration into complex molecular architectures relevant to medicinal chemistry and materials science.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   30.19
  • LogP   0.7106
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

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