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CS-W001157 4
Total: USD 88.00

Desamino lenalidomide-6-COOH

  • CAS No. 2171780-01-9

  • Cat. No. CS-0144945
  • Purity≥98%
  • MDL No.MFCD31735773

*For research and further manufacturing use only, not for direct human use.

Desamino lenalidomide-6-COOH|CS-0144945

Structure of 2171780-01-9

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General Information

  • CAS No. 2171780-01-9
  • Cat. No. CS-0144945
  • Purity ≥98%
  • MDL No. MFCD31735773
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₂N₂O₅
  • Molecular Weight 288.26
  • Synonym(s) None
  • SMILES O=C(O)C1=CC=C2C(=O)N(CC2=C1)C3C(=O)NC(=O)CC3

Description

This isoindoline-based scaffold integrates a piperidinedione moiety and a carboxylic acid group, enabling robust conjugation in bioorthogonal workflows. The structure features high stability under physiological conditions and facilitates efficient coupling to biomolecules via amine-reactive chemistry.

Application

This compound serves as a versatile building block for constructing complex heterocyclic scaffolds, particularly in the synthesis of isoindoline-based pharmaceutical intermediates. Its dioxopiperidine and carboxylic acid functionalities enable sequential functionalization, including nucleophilic substitution and amide coupling reactions. The molecule exhibits good bench stability and facilitates efficient purification, making it well-suited for iterative synthetic workflows in medicinal chemistry and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   103.78
  • LogP   -0.5759
  • H_Acceptors   7
  • H_Donors   2
  • Rotatable_Bonds   2

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