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Structure of 128455-62-9
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5-Chloro-1-methyl-3-(trifluoromethyl)pyrazole-4-carbaldehyde features a trifluoromethyl group and chloro substituent that enhance electron withdrawal, enabling efficient coupling in transition-metal-catalyzed transformations. The aldehyde functionality provides a direct handle for derivatization, while the pyrazole core offers stability under standard reaction conditions.
5-Chloro-1-methyl-3-(trifluoromethyl)pyrazole-4-carbaldehyde serves as a versatile building block in medicinal chemistry, enabling efficient access to functionalized pyrazole scaffolds. The aldehyde group facilitates diverse transformations including reductive amination, Wittig reactions, and nucleophilic additions, while the chloro and trifluoromethyl substituents offer enhanced metabolic stability and modulated electronic properties. Its bench-stable nature and compatibility with standard synthetic protocols make it well-suited for high-throughput library synthesis and process-scale applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: