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CS-W001157 4
Total: USD 88.00

N-(4-Chlorophenyl)hydrazine

  • CAS No. 1073-69-4

  • Cat. No. CS-0059297
  • Purity≥97%
  • MDL No.MFCD00038132

*For research and further manufacturing use only, not for direct human use.

N-(4-Chlorophenyl)hydrazine|CS-0059297

Structure of 1073-69-4

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General Information

  • CAS No. 1073-69-4
  • Cat. No. CS-0059297
  • Purity ≥97%
  • MDL No. MFCD00038132
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇ClN₂
  • Molecular Weight 142.59
  • Synonym(s) 4-Chlorophenylhydrazine
  • SMILES NNC1=CC=C(Cl)C=C1

Description

N-(4-Chlorophenyl)hydrazine features a hydrazine group linked to a para-chlorinated phenyl ring, delivering a potent nucleophilic center for conjugation reactions. This bench-stable compound integrates readily into heterocyclic scaffolds and serves as a key intermediate in the synthesis of azo dyes, pharmaceuticals, and bioactive molecules.

Application

N-(4-Chlorophenyl)hydrazine serves as a reliable building block for the synthesis of hydrazone derivatives and heterocyclic scaffolds, including pyrazoles and triazoles. Its stability under standard bench conditions and compatibility with diverse reaction environments enable efficient coupling and cyclization processes. The para-chloro substituent provides a handle for further functionalization via nucleophilic aromatic substitution, enhancing versatility in medicinal chemistry and materials science applications.

Synthesis

  • Route1
    • null|null
      106-47-8
    • ~58%
    • In-stock
      N-(4-Chlorophenyl)hydrazine|CS-0059297
      1073-69-4

    References

    • Archiv der Pharmazie, , vol. 341, # 5 p. 294 - 300
  • Route2
    • null|null
      106-47-8
    • null|null
      71-36-3
    • ~77%
    • In-stock
      N-(4-Chlorophenyl)hydrazine|CS-0059297
      1073-69-4

    References

    • US6057478 A1, ;
  • Route3
    • null|null
      673-41-6
    • ~63%
    • In-stock
      N-(4-Chlorophenyl)hydrazine|CS-0059297
      1073-69-4

    References

    • Synthetic Communications, , vol. 27, # 4 p. 635 - 639

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P233-P260-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.05
  • LogP   1.6256
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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