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CS-W001157 4
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4-(4-Bromo-2-methylphenyl)morpholine

  • CAS No. 1279032-06-2

  • Cat. No. CS-0153189
  • Molecule weight256.14
  • Purity≥98%
  • MDL No.MFCD20919960

*For research and further manufacturing use only, not for direct human use.

4-(4-Bromo-2-methylphenyl)morpholine|CS-0153189

Structure of 1279032-06-2

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General Information

  • CAS No. 1279032-06-2
  • Cat. No. CS-0153189
  • Purity ≥98%
  • MDL No. MFCD20919960
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₄BrNO
  • Molecular Weight 256.14
  • Synonym(s) 4-(4-Bromo-2-methylphenyl)-morpholine
  • SMILES CC1=CC(=CC=C1N2CCOCC2)Br

Description

4-(4-Bromo-2-methylphenyl)morpholine features a morpholine ring appended to a brominated, methyl-substituted phenyl group, delivering enhanced solubility and metabolic stability. This scaffold integrates well into pharmaceutical discovery workflows, serving as a key building block for kinase inhibitors and bioactive heterocycles.

Application

4-(4-Bromo-2-methylphenyl)morpholine serves as a versatile building block in medicinal chemistry, enabling efficient construction of biologically relevant scaffolds. Its morpholine ring provides favorable solubility and metabolic stability, while the bromo and methyl groups offer orthogonal sites for palladium-catalyzed cross-coupling and functionalization. The compound exhibits excellent bench stability and is compatible with standard reaction conditions, facilitating rapid diversification in target-oriented synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   12.47
  • LogP   2.59412
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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