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CS-W001157 4
Total: USD 88.00

7-Bromoquinolin-3-amine

  • CAS No. 1266322-58-0

  • Cat. No. CS-W006885
  • Purity≥98%
  • MDL No.MFCD20258866

*For research and further manufacturing use only, not for direct human use.

7-Bromoquinolin-3-amine|CS-W006885

Structure of 1266322-58-0

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General Information

  • CAS No. 1266322-58-0
  • Cat. No. CS-W006885
  • Purity ≥98%
  • MDL No. MFCD20258866
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₇BrN₂
  • Molecular Weight 223.07
  • Synonym(s) None
  • SMILES NC1=CC2=CC=C(Br)C=C2N=C1

Description

7-Bromoquinolin-3-amine features a brominated quinoline scaffold with a strategically positioned primary amine, enabling direct coupling in cross-coupling reactions. This bench-stable derivative integrates readily into pharmaceutical and materials synthesis, offering enhanced reactivity compared to non-halogenated analogs.

Application

7-Bromoquinolin-3-amine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its bromo and amino functionalities. The quinoline scaffold provides structural rigidity and favorable pharmacokinetic properties, while the ortho-amino group facilitates further derivatization. Bench-stable and readily purified by crystallization, it functions effectively in Suzuki-Miyaura, Buchwald-Hartwig, and other standard transformations for constructing complex heterocyclic architectures.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   2.5795
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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