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CS-W001157 4
Total: USD 88.00

7-Oxa-4-azaspiro[2.5]octane

  • CAS No. 126616-59-9

  • Cat. No. CS-0058143
  • Purity≥98%
  • MDL No.MFCD09608119

*For research and further manufacturing use only, not for direct human use.

7-Oxa-4-azaspiro[2.5]octane|CS-0058143

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General Information

  • CAS No. 126616-59-9
  • Cat. No. CS-0058143
  • Purity ≥98%
  • MDL No. MFCD09608119
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁NO
  • Molecular Weight 113.16
  • Synonym(s) None
  • SMILES C1CC12COCCN2

Description

7-Oxa-4-azaspiro[2.5]octane features a rigid, bridged heterocyclic core combining oxygen and nitrogen atoms within a spirocyclic framework. This scaffold offers enhanced stability and defined stereochemistry, enabling precise molecular positioning in synthetic applications. The bicyclic structure supports efficient functionalization at key sites while maintaining solubility and compatibility with diverse reaction conditions.

Application

7-Oxa-4-azaspiro[2.5]octane serves as a rigid, bicyclic scaffold enabling precise spatial positioning of functional groups in medicinal chemistry campaigns. Its embedded ether and amine moieties offer orthogonal reactivity for derivatization, while the spirocyclic core provides conformational constraint beneficial for target engagement. The compound exhibits excellent bench stability and facilitates efficient synthesis of diverse heterocyclic systems via standard coupling and cyclization protocols.

Safety Information

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Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   0.1388
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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