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CS-W001157 4
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7-Oxa-4-azaspiro[2.5]octane hydrochloride

  • CAS No. 218595-22-3

  • Cat. No. CS-0080083
  • Purity≥95%
  • MDL No.MFCD18914346

*For research and further manufacturing use only, not for direct human use.

7-Oxa-4-azaspiro[2.5]octane hydrochloride|CS-0080083

Structure of 218595-22-3

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General Information

  • CAS No. 218595-22-3
  • Cat. No. CS-0080083
  • Purity ≥95%
  • MDL No. MFCD18914346
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂ClNO
  • Molecular Weight 149.62
  • Synonym(s) 7-oxa-4-azaspiro[2.5]octane hcl
  • SMILES [H]Cl.C1CC12NCCOC2

Description

7-Oxa-4-azaspiro[2.5]octane hydrochloride features a rigid spirocyclic core with embedded oxygen and nitrogen heteroatoms, delivering enhanced metabolic stability and favorable solubility. This bench-stable scaffold integrates readily into bioactive molecule design, enabling efficient access to constrained analogs in medicinal chemistry campaigns.

Application

7-Oxa-4-azaspiro[2.5]octane hydrochloride serves as a versatile spirocyclic scaffold in medicinal chemistry, enabling efficient construction of complex heterocyclic architectures. Its constrained geometry and dual heteroatoms provide favorable rigidity and polarity for target engagement. The hydrochloride salt enhances solubility and stability, facilitating handling and purification in synthetic workflows. It functions as a key building block in the development of bioactive molecules, particularly within CNS-targeted compounds and kinase inhibitors.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P233-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   0.5606
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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