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CS-W001157 4
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tert-Butyl N-(4-aminopyridin-2-yl)carbamate

  • CAS No. 1266119-48-5

  • Cat. No. CS-0037770
  • Molecule weight209.25
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl N-(4-aminopyridin-2-yl)carbamate|CS-0037770

Structure of 1266119-48-5

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General Information

  • CAS No. 1266119-48-5
  • Cat. No. CS-0037770
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₅N₃O₂
  • Molecular Weight 209.25
  • Synonym(s) Tert-Butyl N-(4-Aminopyridin-2-Yl)Carbamate(WX609350)
  • SMILES CC(C)(C)OC(=O)NC1=CC(=CC=N1)N

Description

tert-Butyl N-(4-aminopyridin-2-yl)carbamate features a protected 4-aminopyridin-2-yl moiety enabling direct incorporation into heterocyclic scaffolds. The tert-butyl carbamate group offers stability under basic conditions while permitting facile deprotection to reveal the primary amine. This derivative serves as a key intermediate in the synthesis of bioactive pyridine-based compounds, particularly in medicinal chemistry applications requiring controlled amine functionality.

Application

tert-Butyl N-(4-aminopyridin-2-yl)carbamate serves as a versatile building block in medicinal chemistry, enabling efficient access to pyridine-based scaffolds. The protected amine facilitates orthogonal functionalization, while the pyridinyl nitrogen supports metal-catalyzed coupling reactions. Its bench-stable nature and compatibility with standard deprotection protocols streamline synthesis of bioactive compounds and heterocyclic intermediates.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   77.24
  • LogP   2.0108
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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