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CS-W001157 4
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N-(5-Methyl-2-oxo-2,3-dihydropyrimidin-4-yl)benzamide

  • CAS No. 126354-30-1

  • Cat. No. CS-0048847
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

N-(5-Methyl-2-oxo-2,3-dihydropyrimidin-4-yl)benzamide|CS-0048847

Structure of 126354-30-1

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General Information

  • CAS No. 126354-30-1
  • Cat. No. CS-0048847
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₁N₃O₂
  • Molecular Weight 229.23
  • Synonym(s) None
  • SMILES CC1=C(NC(=O)C2=CC=CC=C2)NC(=O)N=C1

Description

N-(5-Methyl-2-oxo-2,3-dihydropyrimidin-4-yl)benzamide features a fused dihydropyrimidinone core bearing a methyl group at C5 and a benzoyl substituent at N4. This electron-deficient scaffold integrates readily into heterocyclic synthesis, serving as a key building block for bioactive compound libraries under standard bench conditions.

Application

N-(5-Methyl-2-oxo-2,3-dihydropyrimidin-4-yl)benzamide serves as a versatile building block in medicinal chemistry, enabling the construction of dihydropyrimidine-based scaffolds with demonstrated utility in kinase inhibitor and antiviral agent development. Its amide functionality offers excellent stability and compatibility with standard coupling reactions, while the 5-methyl substitution enhances metabolic resistance. The molecule facilitates efficient derivatization and purification, making it well-suited for high-throughput synthesis and scale-up applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   74.85
  • LogP   1.33062
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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