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(3-Fluoropyridin-2-yl)methanamine hydrochloride

  • CAS No. 1260903-05-6

  • Cat. No. CS-0053366
  • Purity≥97%
  • MDL No.MFCD11505887

*For research and further manufacturing use only, not for direct human use.

(3-Fluoropyridin-2-yl)methanamine hydrochloride|CS-0053366

Structure of 1260903-05-6

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General Information

  • CAS No. 1260903-05-6
  • Cat. No. CS-0053366
  • Purity ≥97%
  • MDL No. MFCD11505887
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈ClFN₂
  • Molecular Weight 162.59
  • Synonym(s) None
  • SMILES NCC1=NC=CC=C1F.[H]Cl

Description

This bench-stable, moisture-tolerant amine features a fluorinated pyridine core that enhances electrophilic reactivity and modulates basicity. The (3-fluoropyridin-2-yl)methanamine hydrochloride integrates readily into synthetic sequences requiring polar, electron-deficient heterocyclic scaffolds, enabling efficient coupling and functionalization under standard conditions.

Application

(3-Fluoropyridin-2-yl)methanamine hydrochloride serves as a versatile building block for medicinal chemistry and catalytic synthesis, enabling direct incorporation of a fluorinated pyridylmethyl moiety into target molecules. The amine functionality facilitates nucleophilic substitution, reductive amination, and coupling reactions under standard conditions. Its bench-stable hydrochloride salt form ensures ease of handling, reproducible reaction performance, and straightforward purification in multistep synthetic sequences.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.1012
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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