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CS-W001157 4
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Boc-N-PEG1-C2-NHS ester

  • CAS No. 1260092-55-4

  • Cat. No. CS-0115067
  • Molecule weight330.33
  • Purity≥97%
  • MDL No.MFCD20227793

*For research and further manufacturing use only, not for direct human use.

Boc-N-PEG1-C2-NHS ester|CS-0115067

Structure of 1260092-55-4

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General Information

  • CAS No. 1260092-55-4
  • Cat. No. CS-0115067
  • Purity ≥97%
  • MDL No. MFCD20227793
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₂N₂O₇
  • Molecular Weight 330.33
  • Synonym(s) None
  • SMILES O=C(ON1C(CCC1=O)=O)CCOCCNC(OC(C)(C)C)=O

Description

Boc-N-PEG1-C2-NHS ester delivers a short, hydrophilic PEG spacer flanked by a stable Boc-protected amine and a reactive NHS ester. This combination enables efficient conjugation to primary amines under physiological conditions while maintaining solubility and stability in aqueous environments.

Application

Boc-N-PEG1-C2-NHS ester serves as a versatile bifunctional linker for peptide and biomolecule conjugation. The NHS ester group readily reacts with primary amines under physiological conditions, while the Boc-protected amine enables subsequent deprotection and further functionalization. Its PEG1 spacer provides enhanced solubility and reduced aggregation, making it ideal for bioconjugation workflows requiring stability, ease of purification, and compatibility with standard synthetic protocols.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   111.24
  • LogP   0.525
  • H_Acceptors   7
  • H_Donors   1
  • Rotatable_Bonds   7

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