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(1S,3R)-3-Aminocyclopentanol hydrochloride

  • CAS No. 1259436-59-3

  • Cat. No. CS-0044036
  • Molecule weight137.61
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(1S,3R)-3-Aminocyclopentanol hydrochloride|CS-0044036

Structure of 1259436-59-3

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General Information

  • CAS No. 1259436-59-3
  • Cat. No. CS-0044036
  • Purity ≥97%
  • MDL No. None
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₂ClNO
  • Molecular Weight 137.61
  • Synonym(s) None
  • SMILES N[C@@H]1CC[C@@H](C1)O.Cl

Description

(1S,3R)-3-Aminocyclopentanol hydrochloride is a chiral cyclopentanol derivative featuring a primary amine group at the 3-position and a bench-stable hydrochloride salt. This configuration delivers enhanced solubility in aqueous systems while maintaining structural integrity under standard handling conditions. The molecule integrates readily into asymmetric synthesis workflows, serving as a stereocontrolled scaffold for pharmaceutical intermediates and catalyst design.

Application

(1S,3R)-3-Aminocyclopentanol hydrochloride serves as a stereochemically defined building block for bioactive molecule synthesis, offering a rigid cyclopentane scaffold with orthogonal functionality. The amine group enables facile derivatization via amidation or alkylation, while the hydroxyl moiety supports selective protection and oxidation. Bench-stable and readily purified by recrystallization, it functions effectively in asymmetric synthesis, peptide mimetics, and medicinal chemistry campaigns requiring constrained chiral intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   0.2803
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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