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3-Aminocyclopentan-1-ol

  • CAS No. 13725-38-7

  • Cat. No. CS-0083804
  • Molecule weight101.15
  • Purity≥97%
  • MDL No.MFCD14705160

*For research and further manufacturing use only, not for direct human use.

3-Aminocyclopentan-1-ol|CS-0083804

Structure of 13725-38-7

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General Information

  • CAS No. 13725-38-7
  • Cat. No. CS-0083804
  • Purity ≥97%
  • MDL No. MFCD14705160
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₁NO
  • Molecular Weight 101.15
  • Synonym(s) Cyclopentanol,3-amino-(7CI,8CI,9CI)
  • SMILES OC1CC(N)CC1

Description

3-Aminocyclopentan-1-ol offers a rigid, cyclopentane scaffold bearing both amine and hydroxyl functionalities, enabling direct incorporation into bioactive molecules. This bifunctional motif supports hydrogen bonding and facilitates solubility in polar solvents, making it valuable for medicinal chemistry and peptide conjugation.

Application

3-Aminocyclopentan-1-ol serves as a versatile chiral building block in medicinal chemistry, enabling access to bioactive heterocycles and conformationally restricted scaffolds. Its hydroxyl and primary amine functionalities offer orthogonal reactivity for selective derivatization, while the rigid cyclopentane core imparts defined stereochemistry. Bench-stable and readily purified, it facilitates efficient synthesis of peptidomimetics and kinase inhibitor intermediates via standard coupling and cyclization protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07,GHS09
Signal Word : Danger
UN#: 3082
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H314-H410
Precautionary Statements : P264-P270-P273-P280-P304+P340-P330-P391-P501

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   -0.1415
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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