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Structure of 1256822-12-4
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5,6,7,8-Tetrahydroquinoline-6-carboxylic acid features a saturated quinoline core with a carboxylic acid at the 6-position, offering enhanced solubility and stability compared to aromatic analogs. This scaffold integrates readily into medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds, where its lipophilic character and hydrogen-bonding capacity support target engagement.
5,6,7,8-Tetrahydroquinoline-6-carboxylic acid serves as a versatile scaffold in medicinal chemistry, enabling the construction of bioactive heterocycles through standard functional group transformations. Its carboxylic acid moiety facilitates direct coupling reactions and derivatization, while the saturated ring system offers enhanced metabolic stability and favorable pharmacokinetic properties. Bench-stable and amenable to purification by recrystallization or chromatography, it functions as a key building block in the synthesis of targeted small molecules and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: