Lot numbers can be found on the outside label of a product:
Methyl 2,4-difluoro-5-nitrobenzoate
-
CAS No. 125568-71-0
- Cat. No. CS-W019417
- Purity≥95%
- MDL No.MFCD07779369
*For research and further manufacturing use only, not for direct human use.
Structure of 125568-71-0
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 125568-71-0
- Cat. No. CS-W019417
- Purity ≥95%
- MDL No. MFCD07779369
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₈H₅F₂NO₄
- Molecular Weight 217.13
- Synonym(s) Benzoic acid, 2,4-difluoro-5-nitro-, methyl ester
- SMILES FC1=C(C(=O)OC)C=C(C(=C1)F)[N+](=O)[O-]
Description
Methyl 2,4-difluoro-5-nitrobenzoate features a trifunctional aromatic core bearing fluorine, nitro, and ester groups. This electron-deficient scaffold enables direct incorporation into cross-coupling reactions and serves as a key building block for bioactive heterocycles. The methyl ester facilitates downstream derivatization under standard conditions.
Application
Methyl 2,4-difluoro-5-nitrobenzoate serves as a versatile building block in medicinal chemistry and agrochemical synthesis. The ortho-fluoro substituents enable directed metalation and facilitate transition-metal-catalyzed cross-coupling reactions, while the nitro group provides a handle for selective reduction and subsequent functionalization. Its bench-stable nature and compatibility with diverse reaction conditions make it ideal for constructing complex heterocyclic scaffolds and multi-functional intermediates.
Synthesis
-
Route1
-
67-56-1 -
In-stock
153775-33-8 - ~99%
-
In-stock
125568-71-0
References
-
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO KG Patent: WO2007/19674 A1, 2007 ; Location in patent: Page/Page column 45 ;
-
-
Route2
-
In-stock
153775-33-8
- ~88%
-
In-stock
125568-71-0
References
-
Shionogi and Co., Ltd. Patent: WO2005/121132 A1, 2005 ; Location in patent: Page/Page column 227-228 ;
-
-
Route3
-
In-stock
106614-28-2 - ~%
-
In-stock
125568-71-0
References
-
US2004/220235 A1, ;
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H319
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 69.44
- LogP 1.6596
- H_Acceptors 4
- H_Donors 0
- Rotatable_Bonds 2
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- Methyl 2,4-difluoro-5-nitrobenzoate sigmaMethyl 2,4-difluoro-5-nitrobenzoate manufacturerMethyl 2,4-difluoro-5-nitrobenzoate priceMethyl 2,4-difluoro-5-nitrobenzoate structureMethyl 2,4-difluoro-5-nitrobenzoate SDSbuy Methyl 2,4-difluoro-5-nitrobenzoateMethyl 2,4-difluoro-5-nitrobenzoate supplierMethyl 2,4-difluoro-5-nitrobenzoate usesMethyl 2,4-difluoro-5-nitrobenzoate molecular weightprice of Methyl 2,4-difluoro-5-nitrobenzoateMethyl 2,4-difluoro-5-nitrobenzoate chemical name formula of Methyl 2,4-difluoro-5-nitrobenzoate