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CS-W001157 4
Total: USD 88.00

(4-Fluoropiperidin-4-yl)methanol hydrochloride

  • CAS No. 1254115-16-6

  • Cat. No. CS-W021103
  • Purity≥95%
  • MDL No.MFCD19105116

*For research and further manufacturing use only, not for direct human use.

(4-Fluoropiperidin-4-yl)methanol hydrochloride|CS-W021103

Structure of 1254115-16-6

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General Information

  • CAS No. 1254115-16-6
  • Cat. No. CS-W021103
  • Purity ≥95%
  • MDL No. MFCD19105116
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₃ClFNO
  • Molecular Weight 169.62
  • Synonym(s) (4-fluoropiperidin-4-yl)methanol,hydrochloride
  • SMILES OCC1(F)CCNCC1.[H]Cl

Description

This bench-stable hydrochloride salt delivers a fluorinated piperidinyl methanol scaffold with enhanced solubility and handling ease. The fluorine substituent imparts metabolic stability, while the primary alcohol enables straightforward derivatization. This compound serves as a key building block in medicinal chemistry for targeted CNS-penetrant drug candidates.

Application

(4-Fluoropiperidin-4-yl)methanol hydrochloride serves as a versatile building block in medicinal chemistry, enabling the construction of fluorinated piperidine scaffolds prevalent in bioactive molecules. The hydrochloride salt enhances solubility and stability, facilitating handling and purification. It functions effectively in nucleophilic substitution and reductive amination reactions, offering reliable access to functionalized intermediates for drug discovery programs.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   32.26
  • LogP   0.4922
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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