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CS-W001157 4
Total: USD 88.00

3-(Hydroxymethyl)cyclobutanol

  • CAS No. 1245647-03-3

  • Cat. No. CS-0186717
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-(Hydroxymethyl)cyclobutanol|CS-0186717

Structure of 1245647-03-3

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General Information

  • CAS No. 1245647-03-3
  • Cat. No. CS-0186717
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₀O₂
  • Molecular Weight 102.13
  • Synonym(s) 3-Hydroxycyclobutanemethanol
  • SMILES C1C(CC1O)CO

Description

3-(Hydroxymethyl)cyclobutanol offers a unique combination of a rigid cyclobutane ring and a pendant hydroxymethyl group, enabling precise spatial control in synthetic transformations. This bench-stable scaffold integrates readily into complex molecular architectures, particularly in the development of strained cyclic systems and bioactive analogs requiring defined stereochemistry and enhanced solubility.

Application

3-(Hydroxymethyl)cyclobutanol serves as a versatile synthetic building block featuring a cyclobutane core with orthogonal hydroxyl and primary alcohol functionalities. Its bench-stable nature facilitates straightforward derivatization, enabling efficient access to functionalized cyclobutane scaffolds via oxidation, protection, or coupling reactions. The molecule functions effectively in standard transformations for medicinal chemistry and materials synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   -0.2504
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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