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Structure of 1242157-15-8
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6-Bromo-8-fluoro-3,4-dihydroisoquinolin-1(2H)-one features a sterically constrained, electron-deficient core that enables direct functionalization at the 3,4-dihydroisoquinoline scaffold. This bench-stable heterocycle integrates seamlessly into medicinal chemistry campaigns targeting CNS agents and kinase inhibitors, offering enhanced metabolic stability and improved solubility profiles under standard conditions.
6-Bromo-8-fluoro-3,4-dihydroisoquinolin-1(2H)-one serves as a versatile building block for the synthesis of bioactive heterocycles, enabling late-stage functionalization via palladium-catalyzed cross-coupling. The bromo and fluoro substituents provide orthogonal reactivity for sequential transformations, while the dihydroisoquinolinone core offers stability and compatibility with diverse reaction conditions. Its bench-stable solid form facilitates handling and purification in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: