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Structure of 1234616-51-3
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tert-Butyl 7-oxo-2,6-diazaspiro[3.4]octane-2-carboxylate features a rigid spirocyclic core with dual nitrogen atoms and a ketone at the C7 position, enabling direct functionalization in heterocyclic synthesis. The tert-butyl ester group enhances solubility and stability under standard conditions, facilitating downstream transformations without protecting-group manipulation. This scaffold serves as a key intermediate for bioactive alkaloid analogs and constrained peptide mimetics.
tert-Butyl 7-oxo-2,6-diazaspiro[3.4]octane-2-carboxylate serves as a versatile spirocyclic building block for the synthesis of nitrogen-containing heterocycles. The molecule features a stable spirocyclic core with orthogonal functional groups: a ketone at C7 and a tert-butyl carbamate at C2, enabling selective transformations. It functions effectively in reductive amination, nucleophilic addition, and transition-metal-catalyzed coupling reactions, offering predictable regiochemistry and high bench stability. Its robustness and compatibility with standard purification methods make it ideal for iterative synthetic workflows in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: