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Structure of 123053-48-5
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(R)-2-Methylpyrrolidine-2-carboxylic acid hydrochloride features a chiral pyrrolidine core with a methyl group at the 2-position, delivering enhanced conformational rigidity. This bench-stable derivative serves as a privileged scaffold in medicinal chemistry, integrating readily into peptidomimetics and bioactive molecule frameworks.
(R)-2-Methylpyrrolidine-2-carboxylic acid hydrochloride serves as a stereochemically defined building block for the synthesis of peptidomimetics and bioactive heterocycles. Its chiral pyrrolidine core exhibits enhanced metabolic stability and conformational rigidity, enabling efficient incorporation into pharmaceutical scaffolds. The hydrochloride salt ensures excellent bench stability, solubility in polar solvents, and ease of handling during solid-phase and solution-phase synthesis. Functions effectively in amide coupling, cyclization, and metal-catalyzed transformations.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: