Imidazo[1,2-c]pyrimidin-7-amine

Name: Imidazo[1,2-c]pyrimidin-7-amine
Brand: ChemScene
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CAS No. 1229383-37-2
Cat. No. CS-0199291
Purity≥95%
MDL No.MFCD19207963

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Imidazo[1,2-c]pyrimidin-7-amine|CS-0199291

Structure of 1229383-37-2

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General Information

CAS No. 1229383-37-2
Cat. No. CS-0199291
Purity ≥95%
MDL No. MFCD19207963
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₆N₄
Molecular Weight None
Synonym(s) 7-aMinoiMidazo[1,2,c]pyriMidine
SMILES C1=CN2C=NC(=CC2=N1)N

Description

Imidazo[1,2-c]pyrimidin-7-amine serves as a privileged scaffold in medicinal chemistry, featuring a fused heterocyclic core that enhances target binding affinity. This electron-rich system integrates readily into kinase inhibitors and antiviral agents, offering improved metabolic stability and solubility under standard conditions.

Application

Imidazo[1,2-c]pyrimidin-7-amine serves as a versatile heterocyclic scaffold in medicinal chemistry, enabling efficient construction of kinase inhibitors and CNS-targeted compounds. Its robust bench stability and tolerance to diverse functional groups facilitate straightforward derivatization via amine alkylation, acylation, or metal-catalyzed coupling reactions. The molecule functions as a key building block for targeted synthesis of bioactive small molecules, particularly in the development of purine analogs and antiviral agents.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

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Computational Chemistry Data

TPSA 56.21
LogP 0.3115
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Imidazole compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrimidine compounds

Key Words

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Imidazo[1,2-c]pyrimidin-7-amine

CAS No. 1229383-37-2

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