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CS-W001157 4
Total: USD 88.00

7-Chloroimidazo[1,2-c]pyrimidine

  • CAS No. 55662-71-0

  • Cat. No. CS-0136587
  • Purity≥97%
  • MDL No.MFCD11043987

*For research and further manufacturing use only, not for direct human use.

7-Chloroimidazo[1,2-c]pyrimidine|CS-0136587

Structure of 55662-71-0

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General Information

  • CAS No. 55662-71-0
  • Cat. No. CS-0136587
  • Purity ≥97%
  • MDL No. MFCD11043987
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄ClN₃
  • Molecular Weight 153.57
  • Synonym(s) None
  • SMILES ClC1=CC2=NC=CN2C=N1

Description

7-Chloroimidazo[1,2-c]pyrimidine serves as a pivotal heterocyclic scaffold in medicinal chemistry, offering a rigid, electron-deficient core that facilitates efficient coupling reactions. This bench-stable compound integrates readily into kinase inhibitors and bioactive small molecules, where its chlorine substituent enables selective functionalization and enhanced target binding through halogen bonding interactions.

Application

7-Chloroimidazo[1,2-c]pyrimidine serves as a versatile building block in medicinal chemistry, enabling efficient construction of purine-like scaffolds and heterocyclic drug candidates. Its electrophilic chlorine atom facilitates nucleophilic substitution under mild conditions, supporting rapid diversification via coupling reactions. The compound exhibits excellent bench stability and compatibility with common functional groups, making it ideal for modular synthesis workflows in API development.

Safety Information

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GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H331
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   30.19
  • LogP   1.3827
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

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