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CS-W001157 4
Total: USD 88.00

3-Bromo-2-(chloromethyl)pyridine

  • CAS No. 122851-69-8

  • Cat. No. CS-0617843
  • Molecule weight206.47
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Bromo-2-(chloromethyl)pyridine|CS-0617843

Structure of 122851-69-8

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General Information

  • CAS No. 122851-69-8
  • Cat. No. CS-0617843
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅BrClN
  • Molecular Weight 206.47
  • Synonym(s) None
  • SMILES ClCC1=NC=CC=C1Br

Description

3-Bromo-2-(chloromethyl)pyridine features a pyridine core functionalized with bromo and chloromethyl groups at adjacent positions, enabling selective cross-coupling and nucleophilic substitution reactions. This bifunctional scaffold facilitates the assembly of complex heterocyclic architectures in medicinal chemistry and materials science.

Application

3-Bromo-2-(chloromethyl)pyridine serves as a versatile bifunctional building block in medicinal chemistry and process development. The chloromethyl group enables nucleophilic substitution reactions, while the bromopyridine moiety supports palladium-catalyzed cross-coupling transformations. Its bench-stable nature and compatibility with diverse functional groups facilitate efficient synthesis of complex heterocyclic scaffolds and targeted API intermediates.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P363-P405-P501

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   2.5829
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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