(R)-3-Isopropylmorpholine hydrochloride

Name: (R)-3-Isopropylmorpholine hydrochloride
Brand: ChemScene
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CAS No. 1227917-52-3
Cat. No. CS-0146951
Molecule weight165.66
Purity≥96%
MDL No.MFCD18382560

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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(R)-3-Isopropylmorpholine hydrochloride|CS-0146951

Structure of 1227917-52-3

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General Information

CAS No. 1227917-52-3
Cat. No. CS-0146951
Purity ≥96%
MDL No. MFCD18382560
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₁₆ClNO
Molecular Weight 165.66
Synonym(s) (R)-3-(1-Methylethyl)-Morpholine HCl
SMILES CC([C@H]1NCCOC1)C.[H]Cl

Description

(R)-3-Isopropylmorpholine hydrochloride is a chiral amine derivative featuring a stereodefined morpholine core with a bulky isopropyl substituent. This configuration imparts enhanced stereocontrol in asymmetric synthesis, particularly in catalytic transformations requiring defined spatial orientation. The hydrochloride salt ensures high solubility and stability under standard bench conditions, enabling reliable use in pharmaceutical process development and chemical biology applications.

Application

(R)-3-Isopropylmorpholine hydrochloride serves as a chiral auxiliary and versatile building block in asymmetric synthesis, enabling stereoselective transformations through its well-defined stereochemistry. The hydrochloride salt enhances solubility and stability in polar reaction media, facilitating efficient coupling reactions and functional group interconversions. Its robust bench stability and compatibility with common protecting group strategies make it ideal for medicinal chemistry campaigns and process development workflows requiring high reproducibility.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

TPSA 21.26
LogP 1.0526
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-3-Isopropylmorpholine hydrochloride

CAS No. 1227917-52-3

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