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CS-W001157 4
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Methyl (R)-morpholine-3-carboxylate

  • CAS No. 1187933-47-6

  • Cat. No. CS-0109445
  • Purity≥96%
  • MDL No.MFCD06799486

*For research and further manufacturing use only, not for direct human use.

Methyl (R)-morpholine-3-carboxylate|CS-0109445

Structure of 1187933-47-6

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General Information

  • CAS No. 1187933-47-6
  • Cat. No. CS-0109445
  • Purity ≥96%
  • MDL No. MFCD06799486
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁NO₃
  • Molecular Weight 145.16
  • Synonym(s) (R)-Methyl morpholine-3-carboxylate
  • SMILES O=C([C@@H]1NCCOC1)OC

Description

Methyl (R)-morpholine-3-carboxylate is a chiral building block featuring a stereodefined morpholine ring with a carboxylate ester at the 3-position. This configuration enables selective incorporation into complex molecular architectures, particularly in medicinal chemistry and asymmetric synthesis. The molecule exhibits enhanced solubility and stability under standard conditions, facilitating efficient downstream transformations without racemization.

Application

Methyl (R)-morpholine-3-carboxylate serves as a chiral building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its morpholine ring enables favorable solubility and metabolic stability, while the ester group facilitates selective transformations. The (R)-stereochemistry provides defined stereocontrol in downstream functionalizations, making it valuable in medicinal chemistry campaigns requiring enantioselective synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   47.56
  • LogP   -0.8522
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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