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CS-W001157 4
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tert-Butyl (2-iodoethyl)carbamate

  • CAS No. 122234-46-2

  • Cat. No. CS-0102471
  • Purity≥95%
  • MDL No.MFCD09951818

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (2-iodoethyl)carbamate|CS-0102471

Structure of 122234-46-2

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General Information

  • CAS No. 122234-46-2
  • Cat. No. CS-0102471
  • Purity ≥95%
  • MDL No. MFCD09951818
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₄INO₂
  • Molecular Weight 271.10
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NCCI

Description

tert-Butyl (2-iodoethyl)carbamate serves as a stable, bench-ready carbamate protecting group for primary amines. The iodoethyl moiety enables efficient copper-catalyzed coupling reactions, facilitating the introduction of diverse functional units. This reagent combines ease of handling with high reactivity in late-stage modifications.

Application

tert-Butyl (2-iodoethyl)carbamate serves as a versatile building block in synthetic organic chemistry, enabling efficient introduction of both iodo and carbamate functionalities. Its stability under standard reaction conditions facilitates use in palladium-catalyzed cross-coupling reactions, while the tert-butyl carbamate group offers reliable protection for primary amines. The molecule functions effectively in C–N bond formation and heterocycle synthesis, with straightforward deprotection via acidolysis to yield the corresponding amine derivative.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302+H312+H332-H314
Precautionary Statements : P260-P264-P270-P271-P280-P301+P330+P331-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   1.9461
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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