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Structure of 1219741-19-1
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5-Chloro-6-iodo-2-(methylsulfonyl)-1H-benzo[d]imidazole features a sterically accessible imidazole core with complementary halogen handles, enabling sequential cross-coupling transformations. The methylsulfonyl group enhances solubility and electronic modulation, while the chloro and iodo substituents provide orthogonal reactivity for palladium-catalyzed diversification under standard conditions.
5-Chloro-6-iodo-2-(methylsulfonyl)-1H-benzo[d]imidazole serves as a versatile building block for late-stage functionalization in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions. The chloro and iodo substituents offer orthogonal reactivity for sequential derivatization, while the methylsulfonyl group enhances solubility and modulates electronic properties. Bench-stable and compatible with standard reaction conditions, it facilitates efficient access to substituted benzimidazole scaffolds relevant to kinase inhibitor and CNS-targeted compound development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: