Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

cis-3-Aminocyclobutanol hydrochloride

  • CAS No. 1219019-22-3

  • Cat. No. CS-W022615
  • Purity≥95%
  • MDL No.MFCD17214231

*For research and further manufacturing use only, not for direct human use.

cis-3-Aminocyclobutanol hydrochloride|CS-W022615

Structure of 1219019-22-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1219019-22-3
  • Cat. No. CS-W022615
  • Purity ≥95%
  • MDL No. MFCD17214231
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₀ClNO
  • Molecular Weight 123.58
  • Synonym(s) 3-Aminocyclobutanol hydrochloride
  • SMILES O[C@H]1C[C@@H](N)C1.[H]Cl

Description

cis-3-Aminocyclobutanol hydrochloride features a strained cyclobutane ring with adjacent amine and hydroxyl groups in a cis configuration, offering enhanced stereochemical control for synthetic applications. This bench-stable salt delivers high solubility in aqueous and protic solvents, enabling efficient incorporation into bioactive molecule scaffolds and chiral building blocks.

Application

cis-3-Aminocyclobutanol hydrochloride serves as a valuable chiral building block in medicinal chemistry, offering a rigid cyclobutane scaffold with orthogonal functional groups. The amine and hydroxyl moieties enable diverse derivatization via amide coupling, etherification, or protection strategies. Its crystalline hydrochloride salt ensures excellent bench stability and ease of handling, facilitating purification and incorporation into complex molecular architectures.

Synthesis

  • Route1

    References

    • AMGEN INC.; ALLEN, Jennifer; FROHN, Michael; HARRINGTON, Paul; PICKRELL, Alexander; RZASA, Robert; SHAM, Kelvin; HU, Essa Patent: WO2011/143366 A1, 2011 ; Location in patent: Page/Page column 144 ; WO 2011/143366 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   46.25
  • LogP   -0.1098
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • cis-3-Aminocyclobutanol hydrochloride sigmacis-3-Aminocyclobutanol hydrochloride manufacturercis-3-Aminocyclobutanol hydrochloride pricecis-3-Aminocyclobutanol hydrochloride structurecis-3-Aminocyclobutanol hydrochloride SDSbuy cis-3-Aminocyclobutanol hydrochloridecis-3-Aminocyclobutanol hydrochloride suppliercis-3-Aminocyclobutanol hydrochloride usescis-3-Aminocyclobutanol hydrochloride molecular weightprice of cis-3-Aminocyclobutanol hydrochloridecis-3-Aminocyclobutanol hydrochloride chemical name formula of cis-3-Aminocyclobutanol hydrochloride
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label