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Structure of 1408074-49-6
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trans-3-Methoxycyclobutanamine hydrochloride is a bench-stable, moisture-tolerant amine derivative featuring a rigid cyclobutane scaffold. The para-methoxy substituent enhances solubility and modulates electronic properties, while the protonated amine enables efficient salt formation. This configuration supports direct incorporation into peptide mimetics and bioactive molecule scaffolds under standard conditions.
trans-3-Methoxycyclobutanamine hydrochloride serves as a valuable chiral building block in medicinal chemistry, offering a rigid, conformationally constrained scaffold. The amine functionality enables direct incorporation into bioactive molecules via standard coupling reactions, while the methoxy group provides moderate electron donation and enhanced solubility. Its crystalline hydrochloride salt form ensures excellent bench stability, ease of handling, and straightforward purification—making it well-suited for high-throughput synthesis and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: