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Structure of 1218791-25-3
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N-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinamide delivers a boronate ester group coupled to a methylated nicotinamide core, enabling efficient Suzuki-Miyaura coupling under standard conditions. This bench-stable reagent integrates readily into complex molecule synthesis, offering enhanced solubility and compatibility with diverse reaction systems.
N-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinamide serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The tetramethylboronate group enables efficient palladium-catalyzed coupling with aryl and heteroaryl halides under mild conditions. Its stability in air and moisture facilitates handling, while the N-methylpyridine scaffold provides orthogonal reactivity for downstream functionalization. This compound is particularly valuable in constructing bioactive heterocyclic frameworks and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: