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Structure of 1141886-36-3
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This boronate moiety integrates a 5-fluoro-6-oxo-1,6-dihydropyridin-3-yl scaffold, offering enhanced stability and compatibility in cross-coupling reactions. The electron-deficient pyridine core facilitates efficient palladium-catalyzed transformations, while the bench-stable boronic acid functionality enables straightforward handling under standard conditions.
(5-Fluoro-6-oxo-1,6-dihydropyridin-3-yl)boronic acid serves as a versatile building block for the synthesis of fluorinated pyridine derivatives. Its boronic acid functionality enables palladium-catalyzed cross-coupling reactions with aryl, vinyl, and heteroaryl halides under mild conditions. The 6-oxo group provides a site for selective functionalization, while the 5-fluoro substituent enhances electrophilicity and facilitates downstream transformations. The compound exhibits good bench stability and is compatible with common protecting groups, making it valuable in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: